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Prescribing Information

TaroCares® can assist with:

  • Coverage and benefit information
  • Prior authorization
  • Co-pay assistance for patients with commercial insurance
  • Hassle-free refills
  • Free delivery
BioPlus

Welcome to TaroCares®!

Once your physician prescribes Taro’s Deferiprone Tablets, he or she will send the prescription to BioPlus for processing.

What’s next?

BioPlus will contact you to set up shipment of your medication and collect your co-pay, if applicable.

IF YOU HAVE ANY QUESTIONS, PLEASE CALL 1-888-292-0744

To report an adverse event for Taro’s Deferiprone Tablets, please call 1-866-923-4914

Commercial Co-Pay Support Program

  • Financial assistance may be available for Taro’s Deferiprone Tablets
    • You may be eligible for co-pay savings on your prescription of Taro's Deferiprone Tablets
  • Eligible patients with commercial insurance may pay as little as $0 per month
  • TaroCares® will pay the remaining co-pay, up to $5,000 per calendar year for eligible patients*

Click to see if you are eligible

* Terms and Conditions apply. This offer is only available to patients with commercial insurance. The program is not available for patients who are enrolled in Medicare, Medicaid, or any other federal or state healthcare program. Taro reserves the right to rescind, revoke, or amend this program without notice. For full Terms and Conditions click here.

To enroll, read the Terms and Conditions for the TaroCares® Commercial Co-Pay Support Program carefully and answer the questions below.

Patient eligibility certification and enrollment (please check all boxes to access co-pay form)

In order to proceed with enrollment, please complete the eligibility certification above.

* Terms & Conditions apply. This offer is only available to patients with commercial insurance. Taro reserves the right to rescind, revoke, or amend this program without notice. For full Terms and Conditions click here.

Please enter patient information

  • You are eligible for the TaroCares Co-pay Coupon that offers savings on your Taro's Deferiprone Tablets prescription when used in accordance with the program's Terms and Conditions.
  • Remember: You’ll need to provide the TaroCares Co-pay Coupon to BioPlus when filling your next prescription.

*Download your TaroCares Co-pay Coupon and print it at your convenience.

Download Your Coupon

Questions about prescription access?

Contact BioPlus

1-888-292-0744
HOURS OF OPERATION
Monday - Friday 8am to 8pm ET

To report an adverse event for Taro’s Deferiprone Tablets, please call 1-866-923-4914

Indication

Deferiprone is an iron chelator indicated for the treatment of patients with transfusional iron overload due to thalassemia syndromes when current chelation therapy is inadequate.

Approval is based on a reduction in serum ferritin levels. There are no controlled trials demonstrating a direct treatment benefit, such as improvement in disease-related symptoms, functioning, or increased survival.

Limitations of Use
Safety and effectiveness have not been established for the treatment of transfusional iron overload in patients with other chronic anemias.

Important Safety Information

WARNING: AGRANULOCYTOSIS AND NEUTROPENIA

  • Deferiprone can cause agranulocytosis that can lead to serious infections and death. Neutropenia may precede the development of agranulocytosis.
  • Measure the absolute neutrophil count (ANC) before starting deferiprone and monitor weekly while on therapy.
  • Interrupt deferiprone if infection develops and monitor the ANC more frequently.
  • Advise patients taking Deferiprone to report immediately any symptoms indicative of infection.

Deferiprone is contraindicated in patients with known hypersensitivity to deferiprone or to any of the excipients in the formulation.

In clinical studies, 7.5% of 642 patients treated with deferiprone developed increased ALT values. Four (0.62%) deferiprone-treated subjects discontinued the drug due to increased serum ALT levels and 1 (0.16%) due to an increase in both ALT and AST. Monitor serum ALT values monthly during therapy with deferiprone and consider interruption of therapy if there is a persistent increase in the serum transaminase levels. Decreased plasma zinc concentrations have been observed on deferiprone therapy. Monitor plasma zinc, and supplement in the event of a deficiency.

Deferiprone can cause fetal harm. Advise females of reproductive potential to use an effective method of contraception during treatment with deferiprone and for at least six months after the last dose. Advise males with female partners of reproductive potential to use effective contraception during treatment with deferiprone and for at least three months after the last dose. Advise females not to breastfeed during treatment with deferiprone and for at least 2 weeks after the last dose.

Avoid co-administration of deferiprone with other drugs known to be associated with neutropenia or agranulocytosis; however, if this is unavoidable, closely monitor the absolute neutrophil count. Avoid co-administration with UGT1A6 inhibitors. Allow at least a 4-hour interval between administration of deferiprone and drugs or supplements containing polyvalent cations (e.g., iron, aluminum, or zinc).

The most common adverse reactions are (incidence ≥5%) nausea, vomiting and abdominal pain, alanine aminotransferase increased, arthralgia, and neutropenia.

Inform patients that their urine might show a reddish/brown discoloration due to the excretion of iron. This is a very common sign of the desired effect, and it is not harmful.

Please see full Prescribing Information, including boxed WARNING and Medication Guide.

Indication

Deferiprone is an iron chelator indicated for the treatment of patients with transfusional iron overload due to thalassemia syndromes when current chelation therapy is inadequate.

Important Safety Information

WARNING: AGRANULOCYTOSIS AND NEUTROPENIA

  • Deferiprone can cause agranulocytosis that can lead to serious infections and death. Neutropenia may precede the development of agranulocytosis.

Indication

Deferiprone is an iron chelator indicated for the treatment of patients with transfusional iron overload due to thalassemia syndromes when current chelation therapy is inadequate.

Approval is based on a reduction in serum ferritin levels. There are no controlled trials demonstrating a direct treatment benefit, such as improvement in disease-related symptoms, functioning, or increased survival.

Limitations of Use
Safety and effectiveness have not been established for the treatment of transfusional iron overload in patients with other chronic anemias.

Important Safety Information

WARNING: AGRANULOCYTOSIS AND NEUTROPENIA

  • Deferiprone can cause agranulocytosis that can lead to serious infections and death. Neutropenia may precede the development of agranulocytosis.
  • Measure the absolute neutrophil count (ANC) before starting deferiprone and monitor weekly while on therapy.
  • Interrupt deferiprone if infection develops and monitor the ANC more frequently.
  • Advise patients taking Deferiprone to report immediately any symptoms indicative of infection.

Deferiprone is contraindicated in patients with known hypersensitivity to deferiprone or to any of the excipients in the formulation.

In clinical studies, 7.5% of 642 patients treated with deferiprone developed increased ALT values. Four (0.62%) deferiprone-treated subjects discontinued the drug due to increased serum ALT levels and 1 (0.16%) due to an increase in both ALT and AST. Monitor serum ALT values monthly during therapy with deferiprone and consider interruption of therapy if there is a persistent increase in the serum transaminase levels. Decreased plasma zinc concentrations have been observed on deferiprone therapy. Monitor plasma zinc, and supplement in the event of a deficiency.

Deferiprone can cause fetal harm. Advise females of reproductive potential to use an effective method of contraception during treatment with deferiprone and for at least six months after the last dose. Advise males with female partners of reproductive potential to use effective contraception during treatment with deferiprone and for at least three months after the last dose. Advise females not to breastfeed during treatment with deferiprone and for at least 2 weeks after the last dose.

Avoid co-administration of deferiprone with other drugs known to be associated with neutropenia or agranulocytosis; however, if this is unavoidable, closely monitor the absolute neutrophil count. Avoid co-administration with UGT1A6 inhibitors. Allow at least a 4-hour interval between administration of deferiprone and drugs or supplements containing polyvalent cations (e.g., iron, aluminum, or zinc).

The most common adverse reactions are (incidence ≥5%) nausea, vomiting and abdominal pain, alanine aminotransferase increased, arthralgia, and neutropenia.

Inform patients that their urine might show a reddish/brown discoloration due to the excretion of iron. This is a very common sign of the desired effect, and it is not harmful.

Please see full Prescribing Information, including boxed WARNING and Medication Guide.